Informational only. Not medical advice.INFORMATIONAL PLATFORM ONLY — NOT MEDICAL ADVICE, DIAGNOSIS, OR TREATMENT
An FDA-approved melanocortin receptor agonist for hypoactive sexual desire disorder in premenopausal women.
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PT-141 received FDA approval based on two Phase III RECONNECT trials (Clayton et al., 2016) in premenopausal women with HSDD. Results showed statistically significant increases in sexual desire and decreases in distress compared to placebo. Earlier research by Diamond et al. demonstrated efficacy in men with erectile dysfunction who did not respond to sildenafil. The drug was originally studied in clinical trials for ED in men before pivoting to female HSDD. Safety monitoring showed transient blood pressure elevations that resolved within 12 hours. Nausea was the most common side effect but typically diminished with repeated dosing.
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Prices verified as of April 2026. Actual prices may vary. For research use only.