Informational only. Not medical advice.INFORMATIONAL PLATFORM ONLY — NOT MEDICAL ADVICE, DIAGNOSIS, OR TREATMENT
A mitochondrial-derived peptide that acts as an exercise mimetic, regulating metabolic homeostasis and cellular stress response.
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$136.86
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vial · 10mghydroresearchpeptides.com
$3.50/mg
43% more per mg
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MOTS-c was discovered by Lee et al. (Cell Metabolism, 2015) and shown to regulate insulin sensitivity and metabolic homeostasis. Studies in diet-induced obese mice demonstrated prevention of obesity and insulin resistance with MOTS-c administration. Kim et al. (2018) showed that MOTS-c translocates to the nucleus under metabolic stress, establishing it as a mitochondrial-to-nuclear signaling peptide. Human studies have shown that circulating MOTS-c levels decline with age and correlate inversely with metabolic disease markers. D'Souza et al. showed that exercise increases circulating MOTS-c, supporting its role as an exercise mimetic. A 2019 study in aging Japanese populations found MOTS-c polymorphisms associated with exceptional longevity.
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Prices verified as of April 2026. Actual prices may vary. For research use only.