Informational only. Not medical advice.INFORMATIONAL PLATFORM ONLY — NOT MEDICAL ADVICE, DIAGNOSIS, OR TREATMENT
Informational only. Not medical advice.INFORMATIONAL PLATFORM ONLY — NOT MEDICAL ADVICE, DIAGNOSIS, OR TREATMENT
A 16-amino-acid mitochondrial-derived peptide (MDP) studied preclinically as a metabolic regulator. Investigational and research-only; not FDA-approved.
3 of 26 vendors lab-verified
Verified purity per dollar — the cheapest that's actually been tested
vial · 40mg· peptidesupplyco.com· price updated today
Lot MC4005192026· tested 2026-05-22
$90.00✓ $2.25/mg
11% more per mg vs cheapest
single-vial price — packs may be lower
vial · 40mg· ngpeptide.com· price updated today
$80.00✓ $2.00/mg
single-vial price — packs may be lower
vial · 40mg· volterasciences.com· price updated today
$99.99✓ $2.50/mg
20% more per mg vs cheapest
single-vial price — packs may be lower
vial · 40mg· peptideplugs.com· price updated today
$100.00✓ $2.50/mg
20% more per mg vs cheapest
single-vial price — packs may be lower
vial · 10mg· retaonelabs.com· price updated today
$31.00−6%
$29.00✓ $2.90/mg
31% more per mg vs cheapest
single-vial price — packs may be lower
vial · 20mg· forgeperformanceco.com· price updated today
$60.00✓ $3.00/mg
33% more per mg vs cheapest
single-vial price — packs may be lower
vial · 30mg· skyepeptides.com· price updated today
$89.00✓ $2.97/mg
33% more per mg vs cheapest
single-vial price — packs may be lower
vial · 40mg· simplepeptide.com· price updated today
$114.00✓ $2.85/mg
30% more per mg vs cheapest
single-vial price — packs may be lower
vial · 10mg· alpha-peptides.com· price updated today
$33.06−17%
$27.55✓ $2.75/mg
27% more per mg vs cheapest
single-vial price — packs may be lower
vial · 40mg· milehighcompounds.is· price updated today
$159.99−13%
$139.99✓ $3.50/mg
43% more per mg vs cheapest
single-vial price — packs may be lower
vial · 20mg· glacieraminos.shop· price updated today
$79.99✓ $4.00/mg
50% more per mg vs cheapest
single-vial price — packs may be lower
vial · 10mg· ionpeptide.com· price updated today
$42.00✓ $4.20/mg
52% more per mg vs cheapest
single-vial price — packs may be lower
vial · 10mg· orosresearch.com· price updated today
Lot OR-LPMOTS10-426-B7· tested 2026-04-16· vendor-declared ✓
$49.99✓ $5.00/mg
60% more per mg vs cheapest
single-vial price — packs may be lower
vial · 20mg· verifiedpeptides.com· price updated today
$77.00✓ $3.85/mg
48% more per mg vs cheapest
single-vial price — packs may be lower
vial · 10mg· orbitrexpeptide.is· price updated today
$49.99✓ $5.00/mg
60% more per mg vs cheapest
single-vial price — packs may be lower
vial · 10mg· peptidology.co· price updated today
$49.00✓ $4.90/mg
59% more per mg vs cheapest
single-vial price — packs may be lower
vial · 10mg· texpeptide.com· price updated today
$45.00✓ $4.50/mg
56% more per mg vs cheapest
single-vial price — packs may be lower
vial · 10mg· ascensionpeptides.com· price updated today
$89.99−46%
$49.00✓ $4.90/mg
59% more per mg vs cheapest
single-vial price — packs may be lower
vial · 10mg· kimerachems.co· price updated 2w ago
$49.99✓ $5.00/mg
60% more per mg vs cheapest
single-vial price — packs may be lower
vial · 10mg· primepeptides.co· price updated today
$55.00✓ $5.50/mg
64% more per mg vs cheapest
single-vial price — packs may be lower
vial · 10mg· eternalpeptides.com· price updated today
$65.00−8%
$59.99✓ $6.00/mg
67% more per mg vs cheapest
single-vial price — packs may be lower
vial · 10mg· optimasupply.is· price updated today
$65.00✓ $6.50/mg
69% more per mg vs cheapest
single-vial price — packs may be lower
vial · 40mg· realpeptides.co· price updated today
$280.00✓ $7.00/mg
71% more per mg vs cheapest
single-vial price — packs may be lower
vial · 5mg· hydroresearchpeptides.com· price updated today
$39.00−10%
$35.00✓ $7.00/mg
71% more per mg vs cheapest
single-vial price — packs may be lower
vial · 10mg· biolongevitylabs.com· price updated today
$109.97✓ $11.00/mg
82% more per mg vs cheapest
single-vial price — packs may be lower
vial · 40mg· crushresearch.shop· price updated today
Lot CR-MOTSC40-2606-BLUE· tested 2026-07-02
$79.00$1.98/mg
single-vial price — packs may be lower
vial · 10mg· virtuspeptides.com· price updated 2d ago
$29.00$2.90/mg
single-vial price — packs may be lower
vial · 10mg· peptidetech.is· price updated today
$44.99$4.50/mg
single-vial price — packs may be lower
37 vendors not shown — trust grade below C, or not enough verified COA data yet. We only list sources with a C grade or better.
Best price trend
Lowest $/mg for MOTS-c · verified listings only
$1.75/mg
▼ 39% over 90d
Reta One Labs has the lowest single-vial MOTS-c price at $1.80/mg among 64 COA-verified vendors on Disclosed Labs. Bulk or multi-vial deals may be lower. That's 84% less per mg than the most expensive option.
What is the price range for MOTS-c?
Research-grade MOTS-c ranges from $1.80/mg to $11.00/mg across 28 verified sources, a 84% spread per mg.
How are MOTS-c prices verified on Disclosed Labs?
Every listed vendor holds a Grade C or better trust score, computed independently from lab Certificates of Analysis — not from payments or sponsorships. Prices are scraped and fact-checked daily. Vendors cannot pay to improve their ranking.
MOTS-c is on the FDA Pharmacy Compounding Advisory Committee (PCAC) July 23–24, 2026 meeting docket for consideration for the Category 1 (503A) authorized compounding list. The PCAC is advisory only — it reviews nominations and makes recommendations; the FDA issues any final rule later. No decision has been made. If eventually added to the Category 1 list, a valid prescription would be required.
Check formulation: Lyophilized powder requires reconstitution before use. Pre-mixed solutions are more convenient but may have a shorter shelf life and higher prices.
Compare per-mg cost: Different strengths and quantities make direct price comparison difficult. Calculate the per-milligram cost to find the true best value.
Verify COAs: Look for vendors that publish per-batch Certificates of Analysis from named, accredited labs. Use the Full safety panel filter to require endotoxin, sterility, and heavy-metals testing on the current batch — not just HPLC purity.
Lee et al. (Cell Metabolism, 2015; PMID 25738459) identified MOTS-c and showed that exogenous administration in mice prevented diet-induced obesity and insulin resistance via AMPK activation in skeletal muscle. Kim et al. (Cell Metabolism, 2018; PMID 29983246) demonstrated that MOTS-c translocates to the nucleus under metabolic stress and regulates antioxidant response element (ARE) genes. Reynolds et al. (Nature Communications, 2021; PMID 33473109) reported that exercise induces MOTS-c in human skeletal muscle and that MOTS-c treatment improved physical capacity in young, middle-aged, and aged mice. Human clinical data are limited to CohBar's Phase 1a/1b study of the analog CB4211 in healthy volunteers and obese NAFLD subjects, which reported acceptable tolerability and exploratory signals on ALT/AST and glucose; CohBar wound down the program in 2023. No completed Phase 2 or Phase 3 trials exist for MOTS-c or its analogs, and grey-market dosing (typically ~10 mg SubQ 2-3x/week) is not clinically validated.
This platform provides informational tools only, not medical advice.
The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance
2015
The Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic Stress
2018
MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis
Prices verified as of July 2026. Actual prices may vary. For research use only.
Single-vial list prices by default for a fair head-to-head — switch to Multi-vial / bulk for pack pricing. Estimates only; verify at vendor before purchase. For research use only. Not medical advice.
2021
Disclosed Labs