Informational only. Not medical advice.INFORMATIONAL PLATFORM ONLY — NOT MEDICAL ADVICE, DIAGNOSIS, OR TREATMENT
Informational only. Not medical advice.INFORMATIONAL PLATFORM ONLY — NOT MEDICAL ADVICE, DIAGNOSIS, OR TREATMENT
P21 (also P021) is a small peptidergic compound — the tetrapeptide core Asp-Gly-Gly-Leu with an N-terminal acetyl and a C-terminal adamantylated glycine amide (Ac-DGGL(A)G-NH2) — derived from an active region (residues ~148–151) of human ciliary neurotrophic factor (CNTF). It was designed and characterized in the Khalid Iqbal laboratory at the New York State Institute for Basic Research in Developmental Disabilities (NYS IBR). It is an experimental, preclinical compound — NOT FDA-approved and NOT tested in humans in published trials. Distinct from the cyclin-dependent kinase inhibitor protein p21/CDKN1A/WAF1 (a completely different gene product; the two share only the name).
0 of 3 vendors lab-verified
Verified purity per dollar — the cheapest that's actually been tested
vial · 10mg· skyepeptides.com· price updated today
$79.00✓ $7.90/mg
single-vial price — packs may be lower
vial · 10mg· simplepeptide.com· price updated today
$198.00✓ $19.80/mg
60% more per mg vs cheapest
single-vial price — packs may be lower
4 vendors not shown — trust grade below C, or not enough verified COA data yet. We only list sources with a C grade or better.
Single-vial list prices by default for a fair head-to-head — switch to Multi-vial / bulk for pack pricing. Estimates only; verify at vendor before purchase. For research use only. Not medical advice.
Best price trend
Lowest $/mg for P21 · verified listings only
$7.90/mg
flat
Skye Peptides has the lowest single-vial P21 price at $7.90/mg among 3 COA-verified vendors on Disclosed Labs. Bulk or multi-vial deals may be lower. That's 60% less per mg than the most expensive option.
What is the price range for P21?
Research-grade P21 ranges from $7.90/mg to $19.80/mg across 3 verified sources, a 60% spread per mg.
How are P21 prices verified on Disclosed Labs?
Every listed vendor holds a Grade C or better trust score, computed independently from lab Certificates of Analysis — not from payments or sponsorships. Prices are scraped and fact-checked daily. Vendors cannot pay to improve their ranking.
Check formulation: Lyophilized powder requires reconstitution before use. Pre-mixed solutions are more convenient but may have a shorter shelf life and higher prices.
Compare per-mg cost: Different strengths and quantities make direct price comparison difficult. Calculate the per-milligram cost to find the true best value.
Verify COAs: Look for vendors that publish per-batch Certificates of Analysis from named, accredited labs. Use the Full safety panel filter to require endotoxin, sterility, and heavy-metals testing on the current batch — not just HPLC purity.
Evidence is preclinical (rodent) only. Key publication: Kazim, Blanchard, Dai, Tung, LaFerla, Iqbal & Iqbal, Neurobiology of Disease 2014 (PMID 25046994) reported that chronic oral P021 rescued cognition, boosted dentate-gyrus neurogenesis, and reduced tau hyperphosphorylation in 3xTg-AD mice. Additional preclinical papers from the Iqbal group (and collaborators) have shown dendritic/synaptic rescue in AD and aging rodent models (e.g., Kazim et al., Alzheimer's Res Ther 2017). No Phase 1/2/3 human trials have been published; no human safety or pharmacokinetic data exist. Grey-market vendor material is unvalidated — purity, identity, and dosing are not verifiable.
This platform provides informational tools only, not medical advice.
Prices verified as of July 2026. Actual prices may vary. For research use only.
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