Informational only. Not medical advice.INFORMATIONAL PLATFORM ONLY — NOT MEDICAL ADVICE, DIAGNOSIS, OR TREATMENT
Coluracetam is a non-peptide small-molecule racetam-family nootropic (pyrrolidinone-substituted tetrahydrofuroquinoline) that enhances high-affinity choline uptake (HACU), the rate-limiting step in acetylcholine synthesis. Originally developed by Mitsubishi Tanabe Pharma as MKC-231 for Alzheimer's disease and later by BrainCells Inc. as BCI-540 for major depressive disorder, it is not FDA-approved for any indication and remains inactive in U.S. regulatory development. Sold only as an unregulated research chemical/nootropic powder with no validated human dose or safety profile.
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No prices found for Coluracetam.
Single-vial list prices by default for a fair head-to-head — switch to Multi-vial / bulk for pack pricing. Estimates only; verify at vendor before purchase. For research use only. Not medical advice.
Kimera Chems has the lowest single-vial Coluracetam price at $0.021/mg among 2 COA-verified vendors on Disclosed Labs. Bulk or multi-vial deals may be lower.
What is the price range for Coluracetam?
Research-grade Coluracetam is listed at $0.021/mg from 1 verified source on Disclosed Labs.
How are Coluracetam prices verified on Disclosed Labs?
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No peer-reviewed or regulatory-posted human efficacy or safety data exist. One Phase 2 randomized, double-blind, placebo-controlled trial (NCT00621270) tested BCI-540 (80 mg once daily or three times daily vs. placebo) in 115 participants with major depressive disorder and concomitant anxiety (Jan 2008–Oct 2009); the trial is listed as Completed but has no results posted (hasResults=false, confirmed via ClinicalTrials.gov). In rodent models, oral coluracetam (1–10 mg/kg) significantly improved Morris water-maze learning deficits in AF64A-lesioned rats without tremor, salivation, or hypothermia, and reversed working-memory deficits and hippocampal acetylcholine depletion in AF64A-treated mice (Bessho et al. 1996, PMID 8740080; Murai et al. 1994, PMID 7710736). Coluracetam is not FDA-approved for any indication; U.S. development for Alzheimer's disease is listed as Inactive.
This platform provides informational tools only, not medical advice.
Safety and Effectiveness Study of BCI-540 Versus Placebo in the Treatment of Major Depressive Disorder With Concomitant Anxiety (NCT00621270)
2008
MKC-231, a choline uptake enhancer: (3) Mode of action of MKC-231 in the enhancement of high-affinity choline uptake
2008
Effect of the novel high affinity choline uptake enhancer ... on deficits of water maze learning in rats
Prices verified as of July 2026. Actual prices may vary. For research use only.
1996