Informational only. Not medical advice.INFORMATIONAL PLATFORM ONLY — NOT MEDICAL ADVICE, DIAGNOSIS, OR TREATMENT
Informational only. Not medical advice.INFORMATIONAL PLATFORM ONLY — NOT MEDICAL ADVICE, DIAGNOSIS, OR TREATMENT
(S)-CE-123 is a non-peptide small molecule belonging to the diphenylmethyl-sulfinyl-thiazole chemotype, structurally related to modafinil. It acts as an atypical, non-releasing dopamine transporter (DAT) inhibitor—blocking dopamine reuptake without triggering amphetamine-like transporter-mediated release. No human clinical data exist; all pharmacology, behavioral, and pharmacokinetic findings are preclinical (rodent in vivo and human-liver-microsome/HEK293-cell in vitro). The compound is not individually named on WADA's current Prohibited List, though modafinil (the parent compound) is a named S6 stimulant; no authoritative WADA ruling specific to CE-123 was found.
Verified purity per dollar — the cheapest that's actually been tested
No prices found for (S)-CE-123.
Single-vial list prices by default for a fair head-to-head — switch to Multi-vial / bulk for pack pricing. Estimates only; verify at vendor before purchase. For research use only. Not medical advice.
Kimera Chems has the lowest single-vial (S)-CE-123 price at $0.018/mg among 2 COA-verified vendors on Disclosed Labs. Bulk or multi-vial deals may be lower.
What is the price range for (S)-CE-123?
Research-grade (S)-CE-123 is listed at $0.018/mg from 1 verified source on Disclosed Labs.
How are (S)-CE-123 prices verified on Disclosed Labs?
Every listed vendor holds a Grade C or better trust score, computed independently from lab Certificates of Analysis — not from payments or sponsorships. Prices are scraped and fact-checked daily. Vendors cannot pay to improve their ranking.
Check formulation: Lyophilized powder requires reconstitution before use. Pre-mixed solutions are more convenient but may have a shorter shelf life and higher prices.
Compare per-mg cost: Different strengths and quantities make direct price comparison difficult. Calculate the per-milligram cost to find the true best value.
Verify COAs: Look for vendors that publish per-batch Certificates of Analysis from named, accredited labs. Use the Full safety panel filter to require endotoxin, sterility, and heavy-metals testing on the current batch — not just HPLC purity.
No human data exist for (S)-CE-123. No registered ClinicalTrials.gov trials or DrugBank entries were found, and the primary source explicitly states that no human data are available. All pharmacology and behavioral data are preclinical. In rats, (S)-CE-123 at 24.0 mg/kg i.p. partially reversed tetrabenazine-induced deficits in effort-based lever pressing, increased progressive-ratio responding, and raised extracellular dopamine in the nucleus accumbens core. At 0.3–1.0 mg/kg i.p., CE-123 improved extra-dimensional set-shifting in an attentional task without the impulsivity-increasing effects observed with R-modafinil at 10 mg/kg. Daily dosing improved spatial memory acquisition and retrieval in a hole-board task and ameliorated maternal-separation-induced spatial learning deficits in adolescent rats, with sex-dependent effects. Pharmacokinetic studies in rats and human liver microsomes show that S-CE-123 achieves ~5-fold greater unbound brain penetration (Kp,uu,brain = 0.5) than R-modafinil but is metabolized 9.3-fold faster in human liver microsomes (t₁/₂ 39 min vs. 364 min).
This platform provides informational tools only, not medical advice.
The Novel Atypical Dopamine Uptake Inhibitor (S)-CE-123 Partially Reverses the Effort-Related Effects of the Dopamine Depleting Agent Tetrabenazine and Increases Progressive Ratio Responding
2019
A Novel Dopamine Transporter Inhibitor CE-123 Improves Cognitive Flexibility and Maintains Impulsivity in Healthy Male Rats
2017
A daily single dose of a novel modafinil analogue CE-123 improves memory acquisition and memory retrieval
Prices verified as of July 2026. Actual prices may vary. For research use only.
2018
Disclosed Labs