Informational only. Not medical advice.INFORMATIONAL PLATFORM ONLY — NOT MEDICAL ADVICE, DIAGNOSIS, OR TREATMENT
Informational only. Not medical advice.INFORMATIONAL PLATFORM ONLY — NOT MEDICAL ADVICE, DIAGNOSIS, OR TREATMENT
Agomelatine is a non-peptide small-molecule naphthalene derivative and melatonin analog that acts as an agonist at MT1/MT2 melatonin receptors and antagonist at serotonin 5-HT2C receptors. It is an EMA-approved prescription antidepressant (Valdoxan, approved February 2009 for major depressive disorder in adults) but is NOT FDA-approved in the United States. Post-marketing surveillance identified hepatotoxicity as an important risk, prompting mandatory liver function monitoring and contraindications in hepatic impairment. Despite its prescription status, agomelatine is sold by gray-market vendors as bulk powder labeled 'for research use only.'
0 of 1 vendors lab-verified
Verified purity per dollar — the cheapest that's actually been tested
vial · 1000mg· kimerachems.co· price updated 3d ago
Lot KC-AGT-02· tested 2025-07-23
$31.99✓ $0.032/mg
single-vial price — packs may be lower
Single-vial list prices by default for a fair head-to-head — switch to Multi-vial / bulk for pack pricing. Estimates only; verify at vendor before purchase. For research use only. Not medical advice.
Kimera Chems has the lowest single-vial Agomelatine price at $0.032/mg among 2 COA-verified vendors on Disclosed Labs. Bulk or multi-vial deals may be lower.
What is the price range for Agomelatine?
Research-grade Agomelatine is listed at $0.032/mg from 1 verified source on Disclosed Labs.
How are Agomelatine prices verified on Disclosed Labs?
Every listed vendor holds a Grade C or better trust score, computed independently from lab Certificates of Analysis — not from payments or sponsorships. Prices are scraped and fact-checked daily. Vendors cannot pay to improve their ranking.
Check formulation: Lyophilized powder requires reconstitution before use. Pre-mixed solutions are more convenient but may have a shorter shelf life and higher prices.
Compare per-mg cost: Different strengths and quantities make direct price comparison difficult. Calculate the per-milligram cost to find the true best value.
Verify COAs: Look for vendors that publish per-batch Certificates of Analysis from named, accredited labs. Use the Full safety panel filter to require endotoxin, sterility, and heavy-metals testing on the current batch — not just HPLC purity.
Agomelatine is an EMA-approved prescription drug for major depressive disorder in adults (approved February 2009, marketed as Valdoxan/Melitor/Thymanax), not an unstudied novel compound. It is NOT FDA-approved in the United States despite completed clinical trials. Pooled human trial data identified hepatotoxicity as an important risk: transaminase elevations >3× upper limit of normal occurred in 1.34% of patients on 25 mg/day and 2.51% on 50 mg/day versus placebo, mostly hepatocellular and idiosyncratic. In rodent studies, chronic agomelatine administration induced regional increases in hippocampal neurogenesis (rat dentate gyrus), normalized stress-suppressed hippocampal neuronal activity and reversed stress-induced decreases in doublecortin expression in chronically stressed rats, and ameliorated stress-induced memory deficits in a mouse chronic social defeat stress model.
This platform provides informational tools only, not medical advice.
Prices verified as of July 2026. Actual prices may vary. For research use only.
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