Informational only. Not medical advice.INFORMATIONAL PLATFORM ONLY — NOT MEDICAL ADVICE, DIAGNOSIS, OR TREATMENT
Informational only. Not medical advice.INFORMATIONAL PLATFORM ONLY — NOT MEDICAL ADVICE, DIAGNOSIS, OR TREATMENT
Head-to-head comparison of Thymalin and Thymogen — mechanism, dosing, side effects, legal status, and pricing.
Thymalin is a heterogeneous polypeptide extract from calf thymus (a mixture, not a single defined peptide) developed in the 1970s by V. Kh. Khavinson and V. G. Morozov at the Military Medical Academy / St. Petersburg Institute of Bioregulation and Gerontology. Registered as a pharmaceutical in the USSR/Russia for immunocorrection. Distinct from Thymulin (Bach's zinc-dependent nonapeptide pGlu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn, originally called FTS) and from Thymosin alpha-1 (a 28-amino-acid synthetic peptide). Not FDA-approved in the US; research-use only.
Thymogen (also marketed as Thymagen) is a synthetic dipeptide, L-Glu-L-Trp (Glu-Trp), originally isolated by the Khavinson group from the calf-thymus polypeptide complex Thymalin and then synthesized. It is registered as a pharmaceutical in Russia for immunocorrection (nasal drops / IM injection). Not FDA-approved in the US; research-use only.
Thymalin
Thymogen
Category
Legal Status
Mechanism
Dose Range
Route
Frequency
Dosing Notes
COA-verified vendors · trust score ≥70 required · single-vial price — bulk/bundle deals may be lower
Thymalin
Thymogen
COA corpus from Disclosed Labs — independently tested batches only.
Thymalin
13
COAs
99.5%
Avg purity
6
Labs
Thymogen
11
COAs
99.7%
Avg purity
5
Labs
Evidence base is almost entirely single-lab (Khavinson/Morozov, St. Petersburg). Long-term observational work in elderly Russian cohorts reported reduced all-cause mortality and lower incidence of respiratory infections with Thymalin (alone or with Epithalamin) over 6–8 years, but these were not blinded Western RCTs and have not been independently reproduced. No FDA-registered clinical trials.
Key references
Evidence base is single-lab (Khavinson and collaborators). A 12-month rat study (Anisimov, Khavinson, Morozov, Biogerontology 2000) reported extended maximum lifespan and reduced spontaneous tumor incidence. Russian clinical reports claim benefit in acute/chronic respiratory infections and post-surgical immunodeficiency; these have not been independently reproduced in Western RCTs.
Key references
Thymalin and Thymogen are both in the Immune category and may have overlapping mechanisms. Researchers should review both profiles carefully, understand the mechanisms of action, and monitor the relevant biomarkers when combining compounds in the same class. As always, consult a licensed healthcare provider before making any decisions about combining research compounds.
This platform provides informational tools only, not medical advice. This comparison is for educational purposes only. Consult a licensed provider.
Side Effects
Contraindications
Lab Testing
Disclosed Labs