IGF-1 (Insulin-like Growth Factor 1)

Overview

Insulin-like Growth Factor 1, a 70-amino-acid peptide hormone that mediates many of growth hormone's anabolic effects. Recombinant IGF-1 (mecasermin) is FDA-approved for severe primary IGF-1 deficiency; non-prescription 'research' use for muscle growth is off-label and unproven.

Mechanism of Action

Binds the IGF-1 receptor to drive cellular proliferation, protein synthesis, and inhibition of apoptosis; in muscle it promotes hypertrophy and satellite-cell activation in animal models.

Research Summary

Strong endocrinology literature for deficiency states; performance/anti-aging use in healthy adults is not supported by controlled human trials and carries growth-signaling risk.

Prescribers who offer IGF-1 (Insulin-like Growth Factor 1)

18 prescribers in our directory work with IGF-1 (Insulin-like Growth Factor 1), each confirmed from their own website. Peptides like IGF-1 (Insulin-like Growth Factor 1) require a prescription from a licensed provider — telehealth options are available.

Reported Side Effects

• Hypoglycemia
• Edema
• Jaw/soft-tissue growth
• Theoretical proliferative risk

Compare IGF-1 (Insulin-like Growth Factor 1) with Others

Frequently asked questions

Has IGF-1 (Insulin-like Growth Factor 1) been independently lab-tested?

Disclosed Labs has collected 1 Certificate of Analysis (COA) for IGF-1 (Insulin-like Growth Factor 1) from 1 independent testing lab. 1 vendor has submitted material for testing. Full testing data is available at https://www.disclosedlabs.com/peptides/igf-1/testing.

Which prescribers offer IGF-1 (Insulin-like Growth Factor 1) with a prescription?

18 prescribers in the Disclosed Labs directory work with IGF-1 (Insulin-like Growth Factor 1), each confirmed from their own website, with telehealth options available. IGF-1 (Insulin-like Growth Factor 1) requires a prescription from a licensed provider. Browse them at https://www.disclosedlabs.com/prescribers?peptide=IGF-1%20(Insulin-like%20Growth%20Factor%201).

How does IGF-1 (Insulin-like Growth Factor 1) work?

Binds the IGF-1 receptor to drive cellular proliferation, protein synthesis, and inhibition of apoptosis; in muscle it promotes hypertrophy and satellite-cell activation in animal models.

What does the research say about IGF-1 (Insulin-like Growth Factor 1)?

Strong endocrinology literature for deficiency states; performance/anti-aging use in healthy adults is not supported by controlled human trials and carries growth-signaling risk.