IGF-1 (Insulin-like Growth Factor 1)

IGF

Compare IGF-1 (Insulin-like Growth Factor 1) prices

Lowest $/mg across vendors

Calculate dosing

Reconstitution

Overview

Insulin-like Growth Factor 1, a 70-amino-acid peptide hormone that mediates many of growth hormone's anabolic effects. Recombinant IGF-1 (mecasermin) is FDA-approved for severe primary IGF-1 deficiency; non-prescription 'research' use for muscle growth is off-label and unproven.

Mechanism of Action

Binds the IGF-1 receptor to drive cellular proliferation, protein synthesis, and inhibition of apoptosis; in muscle it promotes hypertrophy and satellite-cell activation in animal models.

Research Summary

Strong endocrinology literature for deficiency states; performance/anti-aging use in healthy adults is not supported by controlled human trials and carries growth-signaling risk.

Dosing Information

Typical Dose

Research-context dependent

Frequency

Varies

Route

SubQ

Notes

Distinct from IGF-1 LR3 (a longer-acting analog). No validated non-clinical dosing.

Verified testing for IGF-1 (Insulin-like Growth Factor 1)

Aggregated from 1 lab-verified Certificate of Analysis uploaded directly by labs. Purity averages exclude values outside [50%, 100%] to filter unit-misreads.

COAs

Verified labs

Avg purity

—

Endotoxin tested

100%

See every IGF-1 (Insulin-like Growth Factor 1) COA

Reported Side Effects

Hypoglycemia
Edema
Jaw/soft-tissue growth
Theoretical proliferative risk

Contraindications

Active or prior malignancy
Proliferative retinopathy

This platform provides informational tools only, not medical advice. This information is for educational purposes only. Consult a licensed provider.