What is the difference between Cardiogen and Vesugen?

Cardiogen: Cardiogen is a synthetic tetrapeptide (Ala-Glu-Asp-Arg / AEDR) from the Khavinson bioregulator series, studied in Russian preclinical models for potential effects on cardiac-tissue gene expression and... Vesugen: Vesugen is a synthetic tripeptide, Lys-Glu-Asp (KED), from the Khavinson short-peptide 'bioregulator' series, positioned as a short-peptide analog of a bovine vascular-tissue polypeptide complex and c...

Cardiogen vs Vesugen

Q: Can you stack Cardiogen and Vesugen?

Cardiogen (recovery) and Vesugen (recovery) are in the same category and may have overlapping mechanisms — researchers should review both profiles carefully before combining. Consult a licensed provider before combining any compounds.

Head-to-head comparison of Cardiogen and Vesugen — mechanism, side effects, legal status, and pricing.

Cardiogen

Cardiogen is a synthetic tetrapeptide (Ala-Glu-Asp-Arg / AEDR) from the Khavinson bioregulator series, studied in Russian preclinical models for potential effects on cardiac-tissue gene expression and cardiomyocyte structural proteins. Not FDA-approved; no Western clinical trials have been performed, and all published evidence originates from a single research group.

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Vesugen

Vesugen is a synthetic tripeptide, Lys-Glu-Asp (KED), from the Khavinson short-peptide 'bioregulator' series, positioned as a short-peptide analog of a bovine vascular-tissue polypeptide complex and claimed to be vasoprotective. Marketed on the Russian/Ukrainian grey market; not FDA-approved in the US; research-use only.

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Cardiogen

Vesugen

Where Researchers Are Buying

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Cardiogen

Best $/mg

$1.65/mg

Verified PeptidesC

5 trusted vendors listing

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Vesugen

Best $/mg

$2.10/mg

Peptide Supply Co.B

4 trusted vendors listing

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Lab Verification

COA corpus from Disclosed Labs — independently tested batches only.

Cardiogen

COAs

99.5%

Avg purity

Labs

Full testing data

Vesugen

COAs

99.6%

Avg purity

Labs

Full testing data

Cardiogen Research Summary

Evidence is limited to preclinical work from the Khavinson group at the St. Petersburg Institute of Bioregulation and Gerontology. Khavinson et al. (Bull Exp Biol Med, 2012; PMID 22977870) reported that H-Ala-Glu-Asp-Arg-OH increased expression of cytoskeletal and nuclear-matrix proteins in cultured mouse embryonic fibroblasts. There are no independently replicated studies, no randomized controlled trials, and no peer-reviewed evidence of clinical cardioprotective efficacy in humans.

Key references

Tetrapeptide H-Ala-Glu-Asp-Arg-OH stimulates expression of cytoskeletal and nuclear matrix proteins (2012)

Vesugen Research Summary

Evidence base is single-lab (Khavinson/Linkova and collaborators). Preclinical work includes organotypic neuroimmunoendocrine cultures (Bull Exp Biol Med 2012) and endothelial-cell epigenetics studies (Adv Gerontol 2014). No FDA-registered trials; no Western RCTs in vascular disease.

Key references

Can you stack Cardiogen and Vesugen?

Cardiogen and Vesugen are both in the Recovery category and may have overlapping mechanisms. Researchers should review both profiles carefully, understand the mechanisms of action, and monitor the relevant biomarkers when combining compounds in the same class. As always, consult a licensed healthcare provider before making any decisions about combining research compounds.

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This platform provides informational tools only, not medical advice. This comparison is for educational purposes only. Consult a licensed provider.