Informational only. Not medical advice.INFORMATIONAL PLATFORM ONLY — NOT MEDICAL ADVICE, DIAGNOSIS, OR TREATMENT
Head-to-head comparison of ARA-290 and Bronchogen — mechanism, dosing, side effects, legal status, and pricing.
ARA-290 (Cibinetide) is a synthetic 11-amino-acid peptide derived from the helix-B surface of erythropoietin (EPO), developed by Araim Pharmaceuticals. It selectively activates the innate repair receptor (IRR) for anti-inflammatory, tissue-protective, and neuroprotective signaling without stimulating erythropoiesis. ARA-290 is not FDA-approved; it has received FDA Fast Track and Orphan Drug designations for sarcoidosis-associated small fiber neuropathy and remains in clinical development as of April 2026.
ARA-290
Bronchogen
Category
Legal Status
Mechanism
Dose Range
Route
Frequency
Dosing Notes
COA-verified vendors · trust score ≥70 required · single-vial price — bulk/bundle deals may be lower
ARA-290
Bronchogen
COA corpus from Disclosed Labs — independently tested batches only.
ARA-290
36
COAs
99.4%
Avg purity
10
Labs
Bronchogen
9
COAs
99.5%
Avg purity
4
Labs
Dahan et al. (Molecular Medicine, 2013, PMID 24136731) conducted a blinded placebo-controlled trial of 28 days of subcutaneous ARA 290 in sarcoidosis patients with documented small nerve fiber loss; treatment improved neuropathic symptoms, increased corneal nerve fiber density on confocal microscopy, altered thermal thresholds, and improved 6-minute walk distance. Brines et al. (Molecular Medicine, 2015, PMID 25387363) reported a placebo-controlled trial of 4 mg daily SubQ ARA 290 for 28 days in type 2 diabetes: the active arm showed improvements in HbA1c, lipid profile, and PainDetect neuropathic symptom scores, with recovery of intraepidermal nerve fiber measurements versus no change on placebo. Heij et al. (2012) and additional Phase 2 work have supported the tissue-protective signal. ARA-290 has not advanced to Phase 3 registration trials and is not FDA-approved.
Key references
Primarily Russian institutional studies; no large independent controlled human trials.
ARA-290 (Recovery) and Bronchogen (Immune) are in different categories and target different biological pathways. This is a common pattern in multi-compound research protocols. Researchers should monitor the biomarkers from both profiles and watch for interactions listed in each compound’s contraindications. Consult a licensed healthcare provider before combining any research compounds.
This platform provides informational tools only, not medical advice. This comparison is for educational purposes only. Consult a licensed provider.
Side Effects
Contraindications
Lab Testing