Informational only. Not medical advice.INFORMATIONAL PLATFORM ONLY — NOT MEDICAL ADVICE, DIAGNOSIS, OR TREATMENT
GHK-Cu (collagen/elastin remodeling), Melanotan II (melanocyte activation and tanning), and PE-22-28 (follicle-stimulating peptide) target the three pillars of cosmetic peptide research: skin texture, pigmentation, and hair density.
GHK-Cu is a naturally occurring copper-binding tripeptide found in human plasma, saliva, and urine. It is studied extensively for its skin-remodeling, anti-aging, and wound-healing properties, and is widely used in topical cosmetic formulations.
Role: Skin matrix remodeler. The most-studied copper peptide for skin. Stimulates collagen I/III, elastin, and decorin synthesis while reducing MMP-mediated degradation.
Melanotan II is a synthetic analog of alpha-melanocyte-stimulating hormone (α-MSH) that stimulates melanin production, causing skin darkening. It was originally developed at the University of Arizona for preventing skin cancer via increased tanning, but was never FDA-approved.
Role: MC1R/MC4R agonist. Stimulates melanogenesis (tanning) and has secondary appetite and libido effects. Broader receptor activity than Melanotan I.
PE-22-28 is a synthetic peptide fragment derived from proenkephalin that has shown promising results for promoting hair growth. It is studied for its ability to stimulate the dermal papilla cells and extend the anagen (growth) phase of the hair cycle.
Role: Follicle-stimulating peptide studied for hair growth promotion via Wnt/beta-catenin pathway activation in dermal papilla cells.
Use the protocol builder to set doses, frequency, and cycle length. Track your progress with blood work integration.
Start ProtocolFor research purposes only. Not medical advice, diagnosis, or treatment. Consult a licensed provider before making any decisions based on this information.
Anti-Aging & Longevity Stack
Telomeres, mitochondria, and matrix remodeling