Cognitive & Nootropic Stack

Semax (BDNF upregulation), Selank (anxiolytic GABA modulation), and Dihexa (HGF-driven synaptogenesis) are the protocol wizard's nootropic peptide combination. Each targets a distinct neurocognitive pathway — neurotrophic support, anxiety reduction, and synaptic connection formation.

Cognitive3 compounds16 vendors comparedStack from $1610.00

Compounds in this stack

Semax

Semax is a synthetic heptapeptide analog of ACTH(4-10) developed in Russia as a nootropic and neuroprotective agent. It is studied for cognitive enhancement, stroke recovery, and neurodegenerative conditions.

Profile All prices

Role: ACTH 4-10 analog. Promotes BDNF expression and neuronal survival. Studied in ischemic and neurodegenerative preclinical models for cognitive preservation.

200mcgIntranasaldaily

1.Peptide Partners200mg

$1.15/mgBuy

2.Skye Peptides30mg

$2.30/mgBuy

3.Licensed Peptides30mg

$2.57/mgBuy

4.BioLongevity Labs20mg

$3.25/mgBuy

Semax, an ACTH(4-10) analogue, modulates BDNF and trkB expre… (2007)Neuroprotective effects of Semax in conditions of global cer… (2006)Semax modulates the expression of genes related to immune an… (2014)

Selank

Selank is a synthetic analog of the immunomodulatory peptide tuftsin, developed in Russia for its anxiolytic and nootropic properties. It is studied for its ability to reduce anxiety without sedation and enhance cognitive performance.

Profile All prices

Role: Tuftsin analog. Anxiolytic and nootropic peptide that modulates GABA, serotonin, and BDNF pathways without sedation, tolerance, or withdrawal effects.

250mcgIntranasaldaily

1.Peptide Partners600mg

$2.30/mgBuy

2.Felix Chemical Supply10mg

$3.50/mgBuy

Dihexa

Dihexa is a synthetic oligopeptide derivative of angiotensin IV that has been called 'ten million times more potent than BDNF' for its ability to promote new synaptic connections. It is studied for cognitive enhancement and neurodegenerative conditions including Alzheimer's disease.

All prices

Role: HGF/c-Met activator. One of the most potent synaptogenic compounds tested in preclinical memory models. Promotes new synaptic connections at picomolar concentrations.

10mgOraldaily

No vendor pricing available yet.

Dihexa, a HGF/c-Met receptor agonist, rescues cognitive decl… (2013)Hepatocyte growth factor/c-Met signaling in the brain: role … (2014)An angiotensin IV analog enhances cognitive function in rode… (2004)

Build this stack as a protocol

Use the protocol builder to set doses, frequency, and cycle length. Track your progress with blood work integration.

Start Protocol

Other stacks

Healing & Recovery Stack

The classic tissue repair trinity

Fat Loss Stack

GLP agonist + targeted fat metabolism

Growth Hormone Stack

Synergistic GHRH + GHRP for pulsatile GH release

For research purposes only. Not medical advice, diagnosis, or treatment. Consult a licensed provider before making any decisions based on this information.